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Michael Ederer

Mr. Dr.-Ing.
Michael Ederer

 This picture shows Michael Ederer
Phone 0049 711 685-66194
Fax0049 711 685-66371
RoomV9.3.220
Email address
Address
Universität Stuttgart
Institute for System Dynamics
Pfaffenwaldring 9
70569 Stuttgart
Deutschland



Subject:

 I'm interested in the application and development of methods of systems theory in biology (systems biology). In particulary I work on the following topics:

  • Thermodynamic constraints on biochemical network
  • Model reduction
  • Modeling and analysis of signal transduction and metabolic regulation
     
Publications:

Journal Articles:

  • Ederer, Michael, Ernst Dieter Gilles, and Oliver Sawodny. “The Glansdorff-Prigogine stability criterion for biochemical reaction networks.” Automatica In Press, Corrected Proof.
  • Ederer, Michael, and Ernst Dieter Gilles. “Thermodynamically feasible kinetic models of reaction networks.” Biophysical Journal 92, no. 6 (March 15, 2007): 1846-1857.
  • Ederer, Michael, Thomas Sauter, Eric Bullinger, Ernst-Dieter Gilles, and Frank Allgöwer. “An Approach for Dividing Models of Biological Reaction Networks into Functional Units.” SIMULATION 79, no. 12 (December 1, 2003): 703 -716.
  • Feuer, Ronny, Michael Ederer, Ernst-Dieter Gilles, Georg A. Sprenger, Oliver Sawodny, and Thomas Sauter. “Analyse der evolutiven Adaptation am Beispiel einer pyruvat-auxotrophen Escherichia coli-Mutante (Analysis of the Evolutive Adaptation of a Pyruvate-auxotrophic Escherichia coli Mutant).” at - Automatisierungstechnik 56, no. 5 (2008): 257-268.
  • Henkel, Sebastian, Thomas Nägele, Imke Hörmiller, Thomas Sauter, Sawodny, Oliver, Michael Ederer, and Arnd G. Heyer. “A systems biology approach to analyse leaf carbohydrate metabolism in Arabidopsis thaliana.” EURASIP Journal on Bioinformatics and Systems Biology accepted (2011).
  • Koschorreck, Markus, Holger Conzelmann, Sybille Ebert, Michael Ederer, and Ernst Dieter Gilles. “Reduced modeling of signal transduction - a modular approach.” BMC Bioinformatics 8 (2007): 336.
  • Nägele, Thomas, Sebastian Henkel, Imke Hörmiller, Thomas Sauter, Oliver Sawodny, Michael Ederer, and Arnd G Heyer. “Mathematical modeling of the central carbohydrate metabolism in Arabidopsis reveals a substantial regulatory influence of vacuolar invertase on whole plant carbon metabolism.” Plant Physiology 153, no. 1 (May 2010): 260-272.
  • Philippi, Nicole, Dorothee Walter, Rebekka Schlatter, Karine Ferreira, Michael Ederer, Oliver Sawodny, Jens Timmer, Christoph Borner, and Thomas Dandekar. “Modeling system states in liver cells: survival, apoptosis and their modifications in response to viral infection.” BMC Systems Biology 3 (2009): 97.
  • Schlatter, Rebekka, Kathrin Schmich, Ima Avalos Vizcarra, Peter Scheurich, Thomas Sauter, Christoph Borner, Michael Ederer, Irmgard Merfort, and Oliver Sawodny. “ON/OFF and Beyond - A Boolean Model of Apoptosis.” PLoS Comput Biol 5, no. 12 (December 11, 2009): e1000595.
  • Schlatter, Rebekka, Kathrin Schmich, Anna Lutz, Judith Trefzger, Oliver Sawodny, Michael Ederer, and Irmgard Merfort. “Modeling the TNFα-Induced Apoptosis Pathway in Hepatocytes.” PLoS ONE 6, no. 4 (April 20, 2011): e18646.
  • Schmich, Kathrin, Rebekka Schlatter, Nadia Corazza, Karine Sá Ferreira, Michael Ederer, Thomas Brunner, Christoph Borner, and Irmgard Merfort. “Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner.” Hepatology (Baltimore, Md.) 53, no. 1 (January 2011): 282-292.
  • Witt, J., S. Barisic, Oliver Sawodny, Michael Ederer, Dagmar. Kulms, and Thomas Sauter. “ Modeling Time Delay in the NFkappaB Signaling Pathway following Low Dose IL-1 Stimulation.” EURASIP Journal on Bioinformatics and Systems Biology accepted (2011).

Conference Papers:

  • Ederer, M., R. Schlatter, J. Witt, R. Feuer, J. Bona-Lovasz, S. Henkel, and O. Sawodny. “An introduction to kinetic, constraint-based and Boolean modeling in systems biology.” In Control Applications (CCA), 2010 IEEE International Conference on, 129-134, 2010.
  • Ederer, Michael, Eric Bullinger, and Thomas Sauter. “Structuring of the cellular metabolism into functional units with mathematical methods.” In Proc. 3rd European Interdisciplinary School on Nonlinear Dynamics for System and Signal Analysis (June 18-27, 2002), 450-457. Warsaw, Poland, 2004.
  • Ederer, Michael, and Ernst Dieter Gilles. “Thermodynamic-Kinetic Modeling and Electrical Engineering.” In Proceedings of the FOSBE 2007, 135-140. Stuttgart, Germany, 2007.
  • Ederer, Michael, Thomas Sauter, and Ernst Dieter Gilles. “Reduced order modeling of global regulation - Redox regulation in Escherichia coli.” In Proceedings of the FOSBE 2005, 285-288. UCSB, California, USA, 2005.
  • Feuer, R., M. Ederer, N. Trachtmann, T. Sauter, E.D. Gilles, G. Sprenger, and O. Sawodny. “Methods for analysis of evolutive adaptation of E. coli.” In SICE, 2007 Annual Conference, 1359-1365, 2007.
  • Kremling, Andreas, Thomas Sauter, Eric Bullinger, Michael Ederer, Frank Allgöwer, and Ernst Dieter Gilles. “Biosystems Engineering: Applying methods from systems theory to biological systems.” 282-290. Pasadena, CA, USA, 2001.
  • Schlatter, R., D. Knies, M. Ederer, and O. Sawodny. “Analysis of Boolean models using quality assurance methods from software engineering.” In Control Applications (CCA), 2010 IEEE International Conference on, 518-523, 2010. 


Further information:

Open and student/diploma/bachelor/masters theses

We are always interested in students that want to do a work (Studien/Diplom/Bachelor/Masterarbeit) in one of our project. For information on current projects see http://www.isys.uni-stuttgart.de/forschung/sysbio/. For open student theses please see http://www.isys.uni-stuttgart.de/forschung/sysbio/theses/index.html.

Please do not hesitate to contact me, if you are interested in writing a theses in the area of systems biology at the ISYS: